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Fang Zheng Selected Research

Hepatitis

12/2020Hesperetin, a SIRT1 activator, inhibits hepatic inflammation via AMPK/CREB pathway.
7/2019Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response.
1/2019CD8+ T cell/IL-33/ILC2 axis exacerbates the liver injury in Con A-induced hepatitis in T cell-transferred Rag2-deficient mice.
1/2017Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.
2/2015Monitoring liver macrophages using nanobodies targeting Vsig4: concanavalin A induced acute hepatitis as paradigm.
12/2012Blockade of IL-33 ameliorates Con A-induced hepatic injury by reducing NKT cell activation and IFN-γ production in mice.
12/2010High-mobility group box 1 exacerbates concanavalin A-induced hepatic injury in mice.
7/2010Ectopic B7-H4-Ig expression attenuates concanavalin A-induced hepatic injury.
1/2010CpG ODN pretreatment attenuates concanavalin A-induced hepatitis in mice.

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Fang Zheng Research Topics

Disease

93Neoplasms (Cancer)
02/2024 - 03/2004
31Inflammation (Inflammations)
01/2024 - 01/2007
26Cocaine-Related Disorders (Cocaine Addiction)
01/2024 - 03/2013
23Lung Neoplasms (Lung Cancer)
01/2020 - 01/2013
22COVID-19
02/2024 - 01/2020
19Hepatocellular Carcinoma (Hepatoma)
02/2024 - 04/2009
17Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 10/2010
10Neoplasm Metastasis (Metastasis)
01/2024 - 02/2009
10Breast Neoplasms (Breast Cancer)
03/2023 - 04/2004
10Seizures (Absence Seizure)
10/2022 - 04/2007
10Infections
03/2022 - 01/2009
10Rheumatoid Arthritis
07/2019 - 01/2010
9Alzheimer Disease (Alzheimer's Disease)
01/2022 - 11/2004
9Coronary Artery Disease (Coronary Atherosclerosis)
01/2022 - 04/2005
9Hepatitis
12/2020 - 01/2010
8Autoimmune Diseases (Autoimmune Disease)
04/2024 - 12/2010
8Pain (Aches)
01/2023 - 02/2010
7Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
04/2024 - 03/2015
7Ovarian Neoplasms (Ovarian Cancer)
11/2023 - 11/2002
7Carcinogenesis
01/2023 - 09/2005
7Coronary Disease (Coronary Heart Disease)
01/2022 - 04/2004
7Atherosclerosis
01/2022 - 01/2006
6Stomach Neoplasms (Stomach Cancer)
01/2023 - 09/2016
6Melanoma (Melanoma, Malignant)
10/2022 - 09/2011
6Type 2 Diabetes Mellitus (MODY)
01/2022 - 12/2005
6Parkinson Disease (Parkinson's Disease)
01/2022 - 08/2009
6Prostatic Neoplasms (Prostate Cancer)
12/2021 - 11/2016
5Psoriasis (Pustulosis Palmaris et Plantaris)
12/2023 - 01/2019
5Fibrosis (Cirrhosis)
08/2022 - 01/2021
5Multiple Sclerosis
01/2021 - 02/2012
5Substance-Related Disorders (Drug Abuse)
10/2020 - 01/2012
5Cataract (Cataracts)
06/2015 - 03/2008
4Hypoxia (Hypoxemia)
01/2024 - 09/2016
4Wounds and Injuries (Trauma)
07/2023 - 10/2013
4Triple Negative Breast Neoplasms
03/2023 - 01/2020
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2023 - 10/2010
4Body Weight (Weight, Body)
09/2022 - 01/2008
4Carcinoma (Carcinomatosis)
07/2021 - 01/2012
4Schizophrenia (Dementia Praecox)
02/2021 - 06/2012
4Disease Progression
01/2020 - 01/2009
4Nasopharyngeal Carcinoma
01/2019 - 07/2014
4Colitis
01/2019 - 07/2012
4Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
08/2018 - 02/2008
4Ischemia
01/2018 - 06/2008

Drug/Important Bio-Agent (IBA)

55Proteins (Proteins, Gene)FDA Link
02/2024 - 12/2002
25Biomarkers (Surrogate Marker)IBA
12/2023 - 02/2011
22Cocaine (Cocaine HCl)IBA
01/2024 - 03/2013
16HMGB1 Protein (HMG1)IBA
10/2023 - 06/2008
16EnzymesIBA
01/2023 - 12/2011
15Interleukin-33IBA
04/2024 - 07/2012
15DNA (Deoxyribonucleic Acid)IBA
12/2023 - 09/2006
14CytokinesIBA
10/2023 - 12/2012
12MicroRNAs (MicroRNA)IBA
01/2023 - 02/2012
11Messenger RNA (mRNA)IBA
10/2022 - 04/2009
9Retinaldehyde (Retinal)IBA
04/2021 - 01/2017
8Interleukin-6 (Interleukin 6)IBA
10/2023 - 01/2018
8Long Noncoding RNAIBA
01/2020 - 01/2015
7Pilocarpine (Ocusert)FDA LinkGeneric
12/2023 - 08/2009
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2022 - 03/2004
6polyphyllin IIBA
01/2023 - 01/2016
6Single-Domain AntibodiesIBA
01/2022 - 05/2014
6Immunoglobulin G (IgG)IBA
12/2020 - 08/2014
6Cisplatin (Platino)FDA LinkGeneric
01/2020 - 11/2002
5Therapeutic UsesIBA
02/2024 - 01/2016
5LipopolysaccharidesIBA
01/2024 - 06/2008
5Dinoprostone (PGE2)FDA Link
01/2023 - 12/2013
5C-Reactive ProteinIBA
01/2021 - 02/2007
5Interleukin-10 (Interleukin 10)IBA
10/2020 - 01/2007
5cocaine hydrolaseIBA
01/2020 - 05/2014
5oxidized low density lipoproteinIBA
06/2019 - 04/2004
5p38 Mitogen-Activated Protein KinasesIBA
01/2019 - 04/2014
5MethyltransferasesIBA
01/2017 - 03/2015
5Concanavalin AIBA
01/2017 - 01/2010
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2023 - 04/2016
4Phosphotransferases (Kinase)IBA
11/2023 - 09/2012
4Circular RNAIBA
02/2023 - 05/2019
4Opioid Analgesics (Opioids)IBA
01/2023 - 11/2018
4Small Interfering RNA (siRNA)IBA
10/2022 - 01/2014
4Glucose (Dextrose)FDA LinkGeneric
09/2022 - 12/2005
4VaccinesIBA
01/2022 - 04/2012
4BerberineIBA
01/2021 - 04/2014
4Interleukin-17 (Interleukin 17)IBA
01/2021 - 01/2011
4CollagenIBA
01/2021 - 01/2005
4LipidsIBA
01/2020 - 08/2013
4beta-solamarineIBA
11/2019 - 12/2015
4ErbB Receptors (EGF Receptor)IBA
07/2019 - 01/2014
4CalreticulinIBA
07/2019 - 07/2013
4ApolipoproteinsIBA
06/2019 - 11/2004
4Apolipoproteins E (ApoE)IBA
06/2019 - 04/2004
4LDL Receptors (LDL Receptor)IBA
08/2018 - 02/2008
4Amyloid (Amyloid Fibrils)IBA
01/2018 - 01/2014
4Ursolic AcidIBA
05/2016 - 04/2015
4AntigensIBA
01/2016 - 04/2012
4Caspase 3 (Caspase-3)IBA
07/2004 - 11/2002
3Protein Kinases (Protein Kinase)IBA
05/2024 - 06/2014
3Cell-Free Nucleic AcidsIBA
12/2023 - 01/2021

Therapy/Procedure

46Therapeutics
02/2024 - 11/2009
14Drug Therapy (Chemotherapy)
01/2024 - 12/2002
4Immunotherapy
01/2022 - 04/2012
4Radiofrequency Ablation
02/2017 - 10/2010